AUDACITY: A comprehensive approach for the detection and classification of Runs of Homozygosity in medical and population genomics

Runs of Homozygosity (RoHs) are popular among geneticists as the footprint of demographic processes, evolutionary forces and inbreeding in shaping our genome, and are known to confer risk of Mendelian and complex diseases.Notwithstanding growing interest in their study, ELDERBERRY there is unmet need for reliable and rapid methods for genomic analy

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First aid guidelines for fragile contexts (conflict, disaster and remote areas): Contextualization & Adaptation

Topic: In situations of remoteness to medical care, disaster or conflict, first aid provision is important but challenging.Education for learners in such contexts needs to be adapted according to resources available.This paper explores the educational approach and adaptations recommended by the 2020 IFRC First Aid, Resuscitation and Education Guide

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Mycobacterium tuberculosis-Induced Polarization of Human Macrophage Orchestrates the Formation and Development of Tuberculous Granulomas In Vitro.

The tuberculous granuloma is an elaborately organized structure and one of the main histological hallmarks of tuberculosis.Macrophages, which are important immunologic effector and antigen-presenting cells, are the main cell type found in the tuberculous granuloma and have high tweezer plasticity.Macrophage polarization during bacterial infection h

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